Industry
KAIST develops mRNA platform that works well for ageing and obesity
KAIST said a joint research team developed a new mRNA platform by precisely designing the 5\' untranslated region, a key regulatory area that controls how efficiently proteins are produced. Using integrated analysis of large-scale bioinformatics data, the team identified 5\' UTR sequences that improve protein production across diverse cellular environments. In preclinical ageing and obesity models, an mRNA therapeutic based on the design increased protein production and immune responses compared with existing approaches.
